Prostate Cancer

Publication:

Dinesh Singh, et al. "Gene Expression Correlates of Clinical Prostate Cancer Behavior". Cancer Cell, 1:203-209, March, 2002

Raw Data:

(1) http://www-genome.wi.mit.edu/mpr/prostate
(2) http://carrier.gnf.org/welsh/prostate/

Description:

(A) Tumor versus Normal classification: training set (from (1)) contains 52 prostate tumor samples and 50 non-tumor (labelled as "Normal") prostate samples with around 12600 genes. An independent set of testing samples from (2) is also prepared, which is from a different experiment and has a nearly 10-fold difference in overall microarray intensity from the training data. Besides, we have removed extra genes contained in the testing samples. In the above publication, the testing set is indicated to have 27 tumor and 8 normal samples. However, from our extraction, there are 25 tumor and 9 normal samples.
(B) Prediction of clinical outcome: in this data set, 21 patients were evaluable with respect to recurrence following surgery with 8 patients having relapsed and 13 patients having remained relapse free ("non-relapse") for at least 4 years.

Download:

Our transformed .data and .names format files are available here.

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